Dr. Domna Iordanidou was graduated from the department of Chemistry in Aristotle University of Thessaloniki and she received her PhD in the same university in the field of Organic Chemistry. In 2016, in her participation in the program Erasmus+ internship, she worked in the research team of Professor Jean-Luc Reanaud, in the laboratory of Molecular Chemistry and Thioorganics, at the École Nationale Supérieure d’Ingénieurs, in Caen, France.
She has worked in Aristotle University of Thessaloniki in the field of Organic Chemistry and Biochemistry as a postdoctoral researcher. Specifically, she was a collaborator at the Hellenic Center for Small Molecules in the Department of Organic Chemistry and Biochemistry in Aristotle University of Thessaloniki, in the framework of the program “OPENSCREEN-GR: Open access research infrastructure for targeted scanning technologies and bioremediation Livestock, Agriculture and the Environment“. In particular, she dealt with the subject of Chemical Biology with emphasis on the synthesis, development and analysis of new small molecules as modifiers of proteins in order to use them in the study of biological processes and in the discovery of new therapeutic agents. Then, she worked as a postdoctoral researcher at the International University of Greece in the Department of Nutrition and Dietetics in collaboration with Assistant Professor M. Terzidis in the collaboration between Aristotle University of Thessaloniki and International University of Greece. The subject of this collaboration was entitled “Photochemistry in the Dark: a harvest of light from chemically produced Luminosity with the aim of chemical catalysis“. In particular, she studied biomimetic models that act through oxidative stress on biomolecules, and in particular on the synthesis and analysis of DNA base damage. Previously, she worked as a chemistry teacher in private education, while today she works as an Academic Scholar at the International University of Greece, teaching the course Laboratory of Organic Chemistry.
Her research interests focus on catalytic organic reactions using silver (AgNPs) and gold (AuNPs) nanoparticles, but also on organocatalytic methodologies for the synthesis of heterocyclic molecules with possible biological activity. In this context, the kinetics of various reductive reactions were studied, and new reductive pathways for the synthesis of molecules such as dihydroquinoxaline-2-one were developed. Dihydroquinoxaline-2-one is an important target molecule in the treatment of hypertension or inflammation. She has also been involved in the synthesis and study of transition metal complexes, both during her Msc studies and her participation in the Molecular Chemistry and Thioorganics Laboratory at the École Nationale Supérieure d’Ingénieurs, Caen, France. Finally, she has recently focused on biomimetic studies of DNA damage caused by chemiluminescence reactions for possible use in innovative photodynamic therapies.